The Fluor Hanford Campbell Award Business Case Study begins with these words: “It was clear from the first day we arrived on site that the safety system was broken.” This quote from a Fluor employee refers to the Hanford nuclear remediation site in Washington State – a project that Fluor began management of in 1997, inheriting thousands of second- or even third-generation employees at the site. Over the course of this study, readers follow the journey made by Fluor as they implemented radical changes in systems, culture, and ultimately business and EHS performance at a high-profile, high-risk site with roots reaching back to the Manhattan Project of the 1940s.